RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-155
RNA ID
RNA Type
miRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
qRT-PCR; etc.
Target
CRISPLD
Pathway
NA
PubMed ID
Title
HMGB1 induced inflammatory effect is blocked by CRISPLD2 via MiR155 in hepatic fibrogenesis
Year
2016
Function
The inhibitory effect of endotoxin-binding protein crispld depends on the trl4 signaling of mir-155 and is time-dependent. Crispld inhibition can block high mobility group protein 1 (hmgb1) -induced inflammation.